Dolutegravir

Catalogue number: D528800
Chemical name: Dolutegravir
Synonyms: (4R,12aS)-N-[(2,4-Difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-2H-pyrido[1’,2’:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide; GSK 1349572; S/GSK1349572;
CAS Number: 1051375-16-6
Possible CAS #: NA
Molecular form.: C₂₀H₁₉F₂N₃O₅
Appearance: White to Pale Yellow Solid
Melting Point: 188-192°C
Mol. Weight: 419.38
Storage: Refrigerator
Solubility: DMSO (Slightly), Methanol (Sparingly, Heated)
Stability: No Data Available
Category: Anti-virals, Aromatics, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: Dolutegravir is a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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5mg $230.00
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25mg $510.00
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2.5mg $175.00
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10mg $350.00
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50mg $760.00
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Exact Weight Packaging ($75(USD) / Vial)
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Inventory Status:   In Stock

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