N,N’-Diphthaloyl-L-cystine

Catalogue number: D492235
Chemical name: N,N’-Diphthaloyl-L-cystine
Synonyms: L-α,α’-(dithiodimethylene)bis[1,3-dioxo-2-isoindolineacetic Acid; [R-(R*,R*)]-α,α’-[dithiobis(methylene)]bis[1,3-dihydro-1,3-dioxo-2H-isoindole-2-acetic Acid;
CAS Number: 29588-96-3
Possible CAS #: NA
Molecular form.: C₂₂H₁₆N₂O₈S₂
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 500.5
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Amino Acids & Derivatives, Aromatics, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
Boiling Point: No Data Available
Applications: N,N’-Diphthaloyl-L-cystine is used in the synthesis of Di-O-cysteinyl-glycinoyl Curcumin (D455600). Di-O-cysteinyl-glycinoyl curcumin is a metabolite of curcumin (C838500), which is a natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and antioxidant properties. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IκB kinase. Inhibits inducible nitric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelope. C
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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Inventory Status:   Pending QC

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