Catalogue number: D491710
Chemical name: (Z)-1,2-Diphenyl-1-(4-hydroxyphenyl)-1-butene
Synonyms: (Z)-1-(4-Hydroxyphenyl)-1,2-diphenyl-1-butene; (Z)-4-(1,2-Diphenyl-1-butenyl)phenol; ICI 141389; Des-O-dimethylaminoethyl Tamoxifen
CAS Number: 69967-80-2
Possible CAS #: NA
Molecular form.: C₂₂H₂₀O
Appearance: White Solid
Melting Point: No Data Available
Mol. Weight: 300.39
Storage: Refrigerator
Solubility: Dichloromethane, Methanol
Stability: No Data Available
Category: Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: A metabolite of Tamoxifen, that can be biotransformed to a quinone methide, which has the potential to alkylate DNA and may contribute to the genotoxic effects of tamoxifen. This compound slightly increases intracellular free calcium [Ca2+]i in human platelets and partially inhibits thrombin-induced [Ca2+]i elevation.
Dangerous Goods Info: NA
References: Dobrydneva, Y. et al.: J. Cardiovasc. Pharm., 50, 380 (2007); Fan, P. & Bolton, J.: Drug. Metab. Dispos., 29, 891 (2001)
Peer Review Product Citations:

Order Product

  Pack size Price(USD)
100mg $150.00
  Pack size Price(USD)
1g $1200.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   Please Inquire

Search Products:

Enter Catalogue #, CAS # , Chemical Name or Mol Formula:

Search By Category

Search By Category View products by category
Translate »