N-(2,3-Dimethylphenyl)-thiourea is a useful synthetic intermediate in the synthesis of 2-Amino-4,5-dimethylbenzothiazole (A605060); a reagent used in the synthesis of a series of substituted pyrimido[2,1-b]benzothiazoles which exhibit antimicrobial activity. 2-Amino-4,5-dimethylbenzothiazole can also be used as a potential modulator of SKCa, IKCa, and BKCa channels.
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Gupta, S., et al.: Indian J. Chem. B, 48B, 853 (2009); Jensen, B.S., et al. Preparation of 2-aminothiazoles as modulaters of SKCa, IKCa, and BKCa channels. PCT Int. Appl. WO 2000069838 A1 20001123. Nov 23, 2000