Catalogue number: D473525
Chemical name: (1E)-1-[(3’aS,4’R,5’R,6’aR)-5’-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]hexahydro-5,5-dimethylspiro[1,3-dioxane-2,2’(1’H)-pentalen]-4’-yl]-4-methyl-1-octen-6-yn-3-one
Synonyms: [3’aS-[3’aα,4’α(E),5’β,6’aα]]-1-[5’-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]hexahydro-5,5-dimethylspiro[1,3-dioxane-2,2’(1’H)-pentalen]-4’-yl]-4-methyl-1-octen-6-yn-3-one; Spiro[1,3-dioxane-2,2’(1’H)-pentalene], 1-octen-6-yn-3-one deriv.
CAS Number: 116896-29-8
Possible CAS #: NA
Molecular form.: C₂₈H₄₆O₄Si
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 474.75
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Chiral Reagents, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: (1E)-1-[(3’aS,4’R,5’R,6’aR)-5’-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]hexahydro-5,5-dimethylspiro[1,3-dioxane-2,2’(1’H)-pentalen]-4’-yl]-4-methyl-1-octen-6-yn-3-one is an intermediate in the synthesis of Iloprost (I267300),a synthetic analogue of Prostacyclin (PGI2) used to treat pulmonary arterial hypertension (PAH), scleroderma, raynaud’s phenomenon and ischemia.
Dangerous Goods Info: NA
References: Gais, H. J., et al.: Chem. Euro. J., 12, 5610 (2006);
Peer Review Product Citations: Gais, H. J., et al.: Chem. Euro. J., 12, 5610 (2006);

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  Pack size Price(USD)
.25mg $225.00
2.5mg $1350.00
  Pack size Price(USD)
1mg $675.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   Pending QC

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