N-[(2R,4R,5S)-5-[[(1,1-Dimethylethoxy)carbonyl]amino]-4-hydroxy-1-oxo-6- phenyl-2-(phenylmethyl)hexyl]-L-leucyl-L-phenylalaninamide-d5

Catalogue number: D472997
Chemical name: N-[(2R,4R,5S)-5-[[(1,1-Dimethylethoxy)carbonyl]amino]-4-hydroxy-1-oxo-6- phenyl-2-(phenylmethyl)hexyl]-L-leucyl-L-phenylalaninamide-d5
Synonyms: 36: PN: WO2005049027 PAGE: 99 claimed sequence-d5; L 458-d5; L 685458-d5; γ-Secretase Inhibitor X-d5;
CAS Number: NA
Possible CAS #: Unlabeled: 292632-98-5
Molecular form.: C₃₉H₄₇D₅N₄O₆
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 677.88
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: N-[(2R,4R,5S)-5-[[(1,1-Dimethylethoxy)carbonyl]amino]-4-hydroxy-1-oxo-6-phenyl-2-(phenylmethyl)hexyl]-L-leucyl-L-phenylalaninamide-d5, is the labeled analogue of D472995, which is a γ-Secretase Inhibitor, the enzyme complex that catalyzes the cleavage of the amyloid precursor protein (APP) to generate amyloid β-peptide (Aβ), the major causative agent in Alzheimer disease (AD).
Dangerous Goods Info: NA
References: Schedin-Weiss, S., et al.: PLoS One, 8, 63962 (2013); Wanngren, J., et al.: J. Bio. Chem., 287, 32640 (2012);
Peer Review Product Citations:

Order Product

  Pack size Price(USD)
1mg $200.00
  Pack size Price(USD)
10mg $1600.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   Please Inquire

Search Products:

Enter Catalogue #, CAS # , Chemical Name or Mol Formula:

Search By Category

Search By Category View products by category
Translate »