N-[(2R,4R,5S)-5-[[(1,1-Dimethylethoxy)carbonyl]amino]-4-hydroxy-1-oxo-6- phenyl-2-(phenylmethyl)hexyl]-L-leucyl-L-phenylalaninamide

Catalogue number: D472995
Chemical name: N-[(2R,4R,5S)-5-[[(1,1-Dimethylethoxy)carbonyl]amino]-4-hydroxy-1-oxo-6- phenyl-2-(phenylmethyl)hexyl]-L-leucyl-L-phenylalaninamide
Synonyms: 36: PN: WO2005049027 PAGE: 99 claimed sequence; L 458; L 685458; γ-Secretase Inhibitor X
CAS Number: 292632-98-5
Possible CAS #: NA
Molecular form.: C₃₉H₅₂N₄O₆
Appearance: White Solid
Melting Point: 209-211°C
Mol. Weight: 672.85
Storage: Refrigerator
Solubility: Chloroform (Sparingly), DMSO, Methanol
Stability: No Data Available
Category: Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: N-[(2R,4R,5S)-5-[[(1,1-Dimethylethoxy)carbonyl]amino]-4-hydroxy-1-oxo-6-phenyl-2-(phenylmethyl)hexyl]-L-leucyl-L-phenylalaninamide, is a γ-Secretase Inhibitor, the enzyme complex that catalyzes the cleavage of the amyloid precursor protein (APP) to generate amyloid β-peptide (Aβ), the major causative agent in Alzheimer disease (AD).
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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  Pack size Price(USD)
1mg $200.00
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10mg $1600.00
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  Pack size Price(USD)
5mg $965.00
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Exact Weight Packaging ($75(USD) / Vial)
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Inventory Status:   In Stock

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