2,3-Dimethyl-6-amino-2H-indazole Hydrochloride

Catalogue number: D471045
Chemical name: 2,3-Dimethyl-6-amino-2H-indazole Hydrochloride
Synonyms: 2,3-Dimethyl-2H-indazol-6-amine Hydrochloride;
CAS Number: 635702-60-2
Possible CAS #: free base: 444731-72-0
Molecular form.: C₉H₁₂ClN₃
Appearance: Pale Beige Solid
Melting Point: >230°C (dec.)
Mol. Weight: 197.66
Storage: Hygroscopic, Refrigerator, under inert atmosphere
Solubility: DMSO, Methanol
Stability: No Data Available
Category: Metabolites & Impurities
Boiling Point: No Data Available
Applications: 2,3-Dimethyl-6-amino-2H-indazole is an impurity in the synthesis of Pazopanib (P210925) hydrochloride, an oral angiogenesis inhibitor targeting VEGFR and PDGFR.
Dangerous Goods Info: NA
References: Liu, D. et al.: J. Pharm. Biomed. Anal., 50, 144 (2009); Olaussen, K., et al.: Oncogen., 28, 4249 (2009); Sleijfer, S., et al.: J. Clin. Oncol., 27, 3126 (2009); Chan, A., et al.: Drugs, 69, 167 (2009)
Peer Review Product Citations:

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Exact Weight Packaging ($75(USD) / Vial)
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