1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-3-hydroxy-4-(2,4,5-trifluorophenyl)-1-butanone

Catalogue number: D461960
Chemical name: 1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-3-hydroxy-4-(2,4,5-trifluorophenyl)-1-butanone
Synonyms:
CAS Number: 1253056-01-7
Possible CAS #: NA
Molecular form.: C₁₆H₁₄F₆N₄O₂
Appearance: Off-White Solid
Melting Point: No Data Available
Mol. Weight: 408.3
Storage: No Data Available
Solubility: Acetone, Dichloromethane, Methanol
Stability: No Data Available
Category: No Data Available
Boiling Point: No Data Available
Applications: 1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-3-hydroxy-4-(2,4,5-trifluorophenyl)-1-butanone is an intermediate in the synthesis of 3-Desamino-2,3-dehydro Sitagliptin (D281985), which is an impurity of Sitagliptin (S491000); a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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