(1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane Hydrochloride

Catalogue number: D461760
Chemical name: (1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane Hydrochloride
Synonyms: (7S)-3,4-Dimethoxy-N-methyl-bicyclo[4.2.0]octa-1,3,5-triene-7-methanamine Hydrochloride;
CAS Number: 866783-13-3
Possible CAS #: 866783-12-2 free amine
Molecular form.: C₁₂H₁₈ClNO₂
Appearance: White Solid
Melting Point: >216°C (dec.)
Mol. Weight: 243.73
Storage: -20°C Freezer
Solubility: DMSO (Slightly), Methanol (Slightly), Water (Slightly)
Stability: No Data Available
Category: Chiral Reagents, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: (1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane is an intermediate used in preparation of Ivabradine (I940500) which is a selective bradycardic agent with direct effect on the pacemaker If current of the sinoatrial node.
Dangerous Goods Info: NA
References: Thollon,C., et al.: Br. J. Pharmacol., 112, 37 (1994), Ragueneau, I., et al.: Clin. Pharmacol. Ther., 64, 192 (1998), Borer, J.S., et al.: Circulation, 107, 817 (2003), DiFrancesco, D., et al.: Drugs, 64, 1757 (2004)
Peer Review Product Citations:

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  Pack size Price(USD)
250mg $110.00
5g $990.00
  Pack size Price(USD)
1g $330.00
25g $1980.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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