Catalogue number: D461070
Chemical name: 3’,4’-Dimethoxy-α-naphthoflavone
Synonyms: DiMNF; 2-(3,4-Dimethoxyphenyl)-benzo[h]chromen-4-one, NSC 123391; 2-(3,4-Dimethoxyphenyl)-4H-naphtho[1,2-b]pyran-4-one;
CAS Number: 14756-24-2
Possible CAS #: NA
Molecular form.: C₂₁H₁₆O₄
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 332.35
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: 3’,4’-Dimethoxy-α-naphthoflavone (DiMNF) is a potent and selective aryl hydrocarbon receptor (AHR) modulator (SAhRM). Studies show that DiMNF suppresseses cytokine-mediated complement factor gene expression through selective activation of the Ah receptor. DiMNF has therapeutic potential in regulating the immune response to tumor formation.
Dangerous Goods Info: NA
References: Murray, I.A. et al.: Mol. Pharmacol., 79, 508 (2011); Narayanan, G.A. et al.: J. Pharmacol. Exp. Ther., 342, 345 (2012);
Peer Review Product Citations:

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