Catalogue number: D460635
Chemical name: 6,7-Dimethoxy-N-(4-phenoxyphenyl)-4-quinazolinamine
Synonyms: 4-[[4-[[Phenyl]oxy]phenyl]amino]-6,7-dimethoxyquinazoline;
CAS Number: 179248-59-0
Possible CAS #: NA
Molecular form.: C₂₂H₁₉N₃O₃
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 373.4
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Amines, Aromatics, Heterocycles, Inhibitors
Boiling Point: No Data Available
Applications: Src Kinase inhibitor 1. The results showed that SKI-1 induced significant apoptosis in a dose-dependent manner in cancer cells with high basal Src activation. Src promotes survival and invasion of lung cancers with EGF receptor abnormalities and is a potential candidate for mol.-targeted therapy.
Dangerous Goods Info: NA
References: Masaki, T., et al.: Eur. J. Cancer., 39, 1447 (2003), Huang, S., et al.: Clin. Cancer Res., 10, 8195 (2004), Tam, I., et al.: Clin. Cancer Res., 12, 1647 (2006), Tian, et al.: Biochem., 40, 7084 (2001),
Peer Review Product Citations:

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