4,4’-Diisothiocyano-2,2’-stilbenedisulfonic Acid, Disodium Salt

Catalogue number: D460600
Chemical name: 4,4’-Diisothiocyano-2,2’-stilbenedisulfonic Acid, Disodium Salt
Synonyms: DIDS
CAS Number: 67483-13-0
Possible CAS #: NA
Molecular form.: C₁₆H₈N₂Na₂O₆S₄
Appearance: Yellow to Dark Yellow Solid
Melting Point: >300°C (dec.)
Mol. Weight: 498.5
Storage: -20°C Freezer, Under Inert Atmosphere
Solubility: DMSO (Slightly), Methanol (Slightly, Heated)
Stability: Recommend Desiccate and Storage at -20°C
Category: Cross Linking Reagents, Fluorescent Labels & Indicators
Boiling Point: No Data Available
Applications: Stilbene disulfonates have been employed to inhibit anion transport in a large number of mammalian cell types (GABA, Cl-). Some stilbene disulfonates can bind specifically to proteins that are not anion transporters. DIDS reacts with CD4 glycoprotein on T helper lymphocytes and macrophages, blocking HIV type-1 growth at multiple stages of the viral life cycle. Fluorescence: max. Abs. l = 341, max. Em. l = 415 (in water)
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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