Di-O-glycinoylcurcumin Dihydrochloride

Catalogue number: D455700
Chemical name: Di-O-glycinoylcurcumin Dihydrochloride
Synonyms: ((1E,6E)-3,5-Dioxohepta-1,6-diene-1,7-diyl)bis(2-methoxy-4,1-phenylene) bis(2-aminoacetate) Dihydrochloride
CAS Number: 1322544-82-0
Possible CAS #: NA
Molecular form.: C₂₅H₂₈Cl₂N₂O₈
Appearance: Yellow Solid
Melting Point: >127ºC (dec.)
Mol. Weight: 555.4
Storage: Amber Vial, -20°C Freezer, Under inert atmosphere
Solubility: DMSO (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: Aromatics, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Di-O-glycinoylcurcumin Dihydrochloride is a metabolite of curcumin (C838500), which is a natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and antioxidant properties. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IκB kinase. Inhibits inducible nitric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelope. Curcumin is currently being examined as a possible therapeutic for the treatment of Alzheimers dise
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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Exact Weight Packaging ($75(USD) / Vial)
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Inventory Status:   In Stock

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