Di-O-cysteinyl-glycinoyl Curcumin-d6

Catalogue number: D455602
Chemical name: Di-O-cysteinyl-glycinoyl Curcumin-d6
Synonyms: 4-((1E,6E)-7-(4-(2-((R)-2-Amino-3-mercaptopropanamido)acetoxy)-3-methoxyphenyl)-3,5-dioxohepta-1,6-dien-1-yl)-2-methoxyphenyl 2-((S)-2-amino-3-mercaptopropanamido)acetate-d6; 2,2’-[[(1E,6E)-3,5-dioxo-1,6-heptadiene-1,7-diyl]bis(2-methoxy-4,1-phenylene)] Ester L-cysteinyl-glycine-d6;
CAS Number: NA
Possible CAS #: NA
Molecular form.: C₃₁H₃₀D₆N₄O₁₀S₂
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 694.81
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Amino Acids & Derivatives, Aromatics, Inhibitors, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Di-O-cysteinyl-glycinoyl Curcumin-d6 is the isotope labelled analog of Di-O-cysteinyl-glycinoyl Curcumin. Di-O-cysteinyl-glycinoyl curcumin is a metabolite of curcumin (C838500), which is a natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and antioxidant properties. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IκB kinase. Inhibits inducible nitric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelop
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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