1-(4,5-Dihydro-2-thiazolyl)-3-azetidinethiol Hydrochloride

Catalogue number: D454190
Chemical name: 1-(4,5-Dihydro-2-thiazolyl)-3-azetidinethiol Hydrochloride
Synonyms: 1-(4,5-Dihydro-2-thiazolyl)-3-azetidinethiol Monohydrochloride; 2-(3-Mercaptoazetidin-1-yl)-2-thiazoline Hydrochloride; 3-Mercapto-1-(1,3-thiazolin-2-yl)azetidine Hydrochloride
CAS Number: 179337-57-6
Possible CAS #: Free base: 161715-38-4
Molecular form.: C₆H₁₁ClN₂S₂
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 210.75
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Heterocycles, Miscellaneous Reagents, Sulfur & Selenium Compounds
Boiling Point: No Data Available
Applications: 1-(4,5-Dihydro-2-thiazolyl)-3-azetidinethiol Hydrochloride is used as a reagent in the synthesis of Tebipenem Tetrahydrate (T012840); the active metabolite of Tebipenem Pivoxil (T012900) that shows excellent bactericidal activity against β-lactamase-nonproducing, ampicillin-resistant isolates.
Dangerous Goods Info: NA
References: Nakashima, M. et al.: Nip. Kag. Ryo. Gak., 57, 90 (2009); Kishii, K. etal.: Antimicrob. Agents Chemother., 54, 3970 (2010); Xu, Z., et al.: Yaoxue Xuebao, 48, 993 (2013); Hazra, S., et al.: Biochem., 53, 3671 (2014); Li, H., et al.: Int. J. Antimicrob. Ag., 43, 92 (2014)
Peer Review Product Citations:

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