trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene

Catalogue number: D452280
Chemical name: trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene
Synonyms: (±)-trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene; Benzo[a]pyrene-trans-7,8-dihydrodiol; trans-7,8-Dihydro-7,8-dihydroxybenzo[a]pyrene; trans-7,8-Dihydrobenzo[a]pyrene-7,8-diol; trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene; trans-Benzo[a]pyrene-7,8-dihydrodiol
CAS Number: 57404-88-3
Possible CAS #: NA
Molecular form.: C₂₀H₁₄O₂
Appearance: Dark Grey Solid
Melting Point: 165-170°C
Mol. Weight: 286.32
Storage: -20°C Freezer
Solubility: DMSO, Methanol, THF
Stability: No Data Available
Category: Aromatics, Heterocycles, Mutagenesis Research Chemicals
Boiling Point: No Data Available
Applications: trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene is a metabolite of Benzopyrene (B205800). Benzo[a]pyrene (B205800), a prototypic PAH, is metabolized by cytochrome P 450 1A1/1B1. (-)-trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene (D452280) undergoes further P 4501A1/1B1-mediated metabolism to a carcinogen, which forms DNA-adducts primarily with 2’-deoxyguanosine. A carcinogen.
Dangerous Goods Info: Not a dangerous good if item is equal too or less than 1g/ml and there is less than 100g in the package
References:
Peer Review Product Citations:

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