(2Z)-1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-2-buten-1-one

Catalogue number: D450690
Chemical name: (2Z)-1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-2-buten-1-one
Synonyms:
CAS Number: 1803026-54-1
Possible CAS #: NA
Molecular form.: C₁₆H₁₂F₆N₄O
Appearance: Light Yellow Oil
Melting Point: No Data Available
Mol. Weight: 390.28
Storage: No Data Available
Solubility: Chloroform, DCM, Methanol
Stability: No Data Available
Category: No Data Available
Boiling Point: No Data Available
Applications: (2Z)-1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-2-buten-1-one is an intermediate in the synthesis of 3-Desamino-2,3-dehydro Sitagliptin (D281985),an impurity of Sitagliptin (S491000). Sitagliptin is a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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