4α,5-Dihydro Simvastatin

Catalogue number: D450010
Chemical name: 4α,5-Dihydro Simvastatin
Synonyms: (1S,3S,4aR,7S,8S,8aS)-8-(2-((2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-3,7-dimethyl-1,2,3,4,4a,7,8,8a-octahydronaphthalen-1-yl 2,2-dimethylbutanoate; Simvastatin Impurity K
CAS Number: NA
Possible CAS #: NA
Molecular form.: C₂₅H₄₀O₅
Appearance: White to Off-White Solid
Melting Point: 148-152°C
Mol. Weight: 420.58
Storage: Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility: Acetonitrile (Slightly, Heated), Chloroform (Slightly)
Stability: No Data Available
Category: Chiral Reagents, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: 4α,5-Dihydro Simvastatin is an impurity in the synthesis of Simvastatin (S485000), a synthetic derivative of a fermentation product of Aspergillus terreus. A competitive inhibitor of HMG-CoA reductase. A synthetic analog of Lovastatin. Antilipemic. Simvastatin, the drug, is sold under the trade name Zocor.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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