trans (2,3)-Dihydro Tetrabenazine

Catalogue number: D449655
Chemical name: trans (2,3)-Dihydro Tetrabenazine
Synonyms: rel-(2R,3R,11bR)-1,3,4,6,7,11b-Hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-ol; (2α,3β,11bβ)-1,3,4,6,7,11b-Hexahydro-9,10-dimethoxy-3 -(2-methylpropyl)-2H-benzo[a]quinolizin-2-ol;
CAS Number: 171598-74-6
Possible CAS #: NA
Molecular form.: C₁₉H₂₉NO₃
Appearance: White Solid
Melting Point: 167-170°C
Mol. Weight: 319.44
Storage: Refrigerator
Solubility: Chloroform
Stability: No Data Available
Category: Chiral Reagents, Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: A metabolite of Tetrabenazine in vivo. The trans izomer of Dihydrotetrabenazine is used for the treatment of hyperkinetic movement disorders.
Dangerous Goods Info: NA
References: Kilbourn, M., et al.: Eur. J. Pharmacol., 278, 249 (1995), Perera, R., et al.: J. Med. Chem., 46, 2599 (2003), Mager, D., et al.: J. Pharm. Sci., 94, 2475 (2005), Zheng, G., et al.: Bioorg. Med. Chem., 16, 5018 (2006),
Peer Review Product Citations:

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