2,2-Difluoroethyl Triflate

Catalogue number: D448130
Chemical name: 2,2-Difluoroethyl Triflate
Synonyms: Trifluoro-methanesulfonic Acid 2,2-difluoroethyl Ester; 2,2-Difluoroethyl Trifluoromethanesulfonate; Trifluoromethanesulfonic Acid 2,2-Difluoroethyl Ester
CAS Number: 74427-22-8
Possible CAS #: NA
Molecular form.: C₃H₃F₅O₃S
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 214.11
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Sulfur & Selenium Compounds
Boiling Point: No Data Available
Applications: 2,2-Difluoroethyl Triflate is used to prepare kinesin spindle protein inhibitors for treatment of taxane-refractory cancer. It is also used to synthesize MexAB-​OprM specific efflux pump inhibitors in Pseudomonas aeruginosa.
Dangerous Goods Info: NA
References: Cox, C., et al.: J. Med. Chem., 51,4239 (2008); Yoshida, K., et al.: Bioorg. Med. Chem., 14, 8506 (2006)
Peer Review Product Citations:

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