Dimethyl 2-(Methoxymethylene)malonate

Catalogue number: D447505
Chemical name: Dimethyl 2-(Methoxymethylene)malonate
Synonyms: Dimethyl methoxymethylenemalonate; NSC 131266
CAS Number: 22398-14-7
Possible CAS #: NA
Molecular form.: C₇H₁₀O₃
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 142.15
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Miscellaneous Reagents
Boiling Point: No Data Available
Applications: Dimethyl 2-(Methoxymethylene)malonate is a useful synthetic intermediate. It is used in preparation of (phenoxyethoxy)quinolones with antimalarial activities. It is also a reagent used in the synthesis of bicyclic pyridones prepn. as oral selective CB2 agonists with anti-pruritic activity.
Dangerous Goods Info: NA
References: Cross, M., et al.: J. Med. Chem., 54, 8321 (2011); Kusakabe, K., et al.: Bioorg. Med. Chem., 21, 3154 (2013)
Peer Review Product Citations:

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