(7R)-3,4-Dimethoxy-N-methyl-bicyclo[4.2.0]octa-1,3,5-triene-7-methanamine Hydrochloride

Catalogue number: D446980
Chemical name: (7R)-3,4-Dimethoxy-N-methyl-bicyclo[4.2.0]octa-1,3,5-triene-7-methanamine Hydrochloride
Synonyms: Ivabradine Impurity
CAS Number: 1204612-29-2
Possible CAS #: Free Base:1132667-04-9
Molecular form.: C₁₂H₁₈ClNO₂
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 243.73
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: No Data Available
Boiling Point: No Data Available
Applications: (7R)-3,4-Dimethoxy-N-methyl-bicyclo[4.2.0]octa-1,3,5-triene-7-methanamine is an impurity of Ivabradine (I940500) which is used as a medication for angina and is a selective bradycardic agent with direct effect on the pacemaker If current of the sinoatrial node.
Dangerous Goods Info: NA
References: Mou, S., et al.: Normal phase high performance liquid chromatography (HPLC) method for rapidly analyzing and separating ivabradine hydrochloride intermediate and its optical isomer, China Patent 101609071, Dec 23, 2009; Thollon,C., et al.: Br. J. Pharmacol., 112, 37 (1994), Ragueneau, I., et al.: Clin. Pharmacol. Ther., 64, 192 (1998), Borer, J.S., et al.: Circulation, 107, 817 (2003), DiFrancesco, D., et al.: Drugs, 64, 1757 (2004),
Peer Review Product Citations:

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