N-Didesmethyl Loperamide-d4

Catalogue number: D441137
Chemical name: N-Didesmethyl Loperamide-d4
Synonyms: 4-(4-Chlorophenyl)-4-hydroxy-α,α-diphenyl-1-piperidinebutanamide-d4; R 21345-d4
CAS Number: NA
Possible CAS #: Unlabelled: 66164-06-5
Molecular form.: C₂₇H₂₅D₄ClN₂O₂
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 453.01
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Amines, Aromatics, Heterocycles, Isotope Labelled Compounds, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: N-Didesmethyl Loperamide-d4 is the isotope labelled analog of N-Didesmethyl Loperamide (D441135); a metabolite of the antidiarrheal Loperamide (L469450, HCl). Also a new and improved PET radiotracer for imaging P-gp function.
Dangerous Goods Info: Not a dangerous good if item is equal too or less than 1g/ml and there is less than 100g in the package
References: Stokbroekx, et al.: J. Med. Chem., 1, 782 (1973); Carter, J.E., et al.: Anal. Profiles Drug Subs., 19, 341 (1990); Rahman, A., et al.: Cancer Res., 54, 5543 (1994); Sai, Y., et al.: Xenobiotica, 30, 327 (2000); Eneroth, A., et al.: Eur. J. Pharm. Sci., 12, 205 (2001); Kim, K., et al.: Drug Metab. Dispos., 31, 1090 (2003)
Peer Review Product Citations:

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