4-[(3,5-Dichloro-4-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile

Catalogue number: D435380
Chemical name: 4-[(3,5-Dichloro-4-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile
Synonyms: Des(2,4-dichloro-5-methoxyphenyl) 3,5-Dichloro-4-methoxyphenyl Bosutinib
CAS Number: 1391063-17-4
Possible CAS #: NA
Molecular form.: C₂₆H₂₉Cl₂N₅O₃
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 530.45
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: No Data Available
Boiling Point: No Data Available
Applications: Kinase inhibitors, such as bosutinib, are useful cancer drugs but their target specificity is not fully understood. 4-[(3,5-Dichloro-4-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile has been employed as a clinical kinase inhibitor bosutinib to elucidate the recognition mechanism between the ATP-binding site and the compound.  
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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