Catalogue number: D434235
Chemical name: (S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol
Synonyms: (αS)-2,6-Dichloro-3-fluoro-α-methylbenzenemethanol
CAS Number: 877397-65-4
Possible CAS #: NA
Molecular form.: C₈H₇Cl₂FO
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 209.04
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Intermediates, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: (S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol is an intermediate in the synthetic preparation of Crizotinib (C785000), a potent and selective dual inhibitor of mesenchymal-epithelial transition factor (c-MET) kinase and anaplastic lymphoma kinase (ALK). Crizotinib is a potential antitumor agent.
Dangerous Goods Info: NA
References: De, Koning, P.D., et al.: Org. Proc. Res. Develop., 15, 1018 (2011); Nishii, H., et al.: Bioorg. Med. Chem. Lett., 20, 1405 (2010);
Peer Review Product Citations:

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