Catalogue number: D431595
Chemical name: 2,3’-Dichloroacetophenone
Synonyms: 2-Chloro-1-(3-chlorophenyl)-1-ethanone; 2-Chloro-1-(3-chlorophenyl)ethanone; 2’-Chloro-3-chloroacetophenone; 3-Chlorophenacyl Chloride; m-Chlorophenacyl Chloride
CAS Number: 21886-56-6
Possible CAS #: NA
Molecular form.: C₈H₆Cl₂O
Appearance: Light Brown Solid
Melting Point: 40-42°C
Mol. Weight: 189.04
Storage: Refrigerator, under inert atmosphere
Solubility: Chloroform (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: Aromatics, Miscellaneous Reagents
Boiling Point: No Data Available
Applications: 2,3’-Dichloroacetophenone is used as a reagent in the synthesis of benzothiazepinones (BTZs) as novel non-ATP competitive inhibitors of glycogen synthase kinase-3β (GSK-3β). Also used as a reagent in the synthesis of benzimidazolyl pyridinones as insulin-like growth factor I (IGF-1R) kinase inhibitors.
Dangerous Goods Info: NA
References: Zhang, P., et al.: Eur. J. Med. Chem., 61, 95 (2013); Wittman, M.D., et al.: Bioorg. Med. Chem. Lett., 17, 974 (2007)
Peer Review Product Citations:

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