Dexrazoxane

Catalogue number: D299050
Chemical name: Dexrazoxane
Synonyms: 4,4’-[(1S)-1-Methyl-1,2-ethanediyl]bis-2,6-piperazinedione; (S)-4,4’-(1-Methyl-1,2-ethanediyl)bis-2,6-piperazinedione; (+)-4,4’-Propylenedi-2,6-piperazinedione; (+)-1,2-Bis(3,5-dioxopiperazin-1-yl)propane; (S)-(+)-1,2-Bis(3,5-dioxopiperazin-1-yl)propane; ADR 529; ICRF 187; NSC 169780; Savene; Totect; Zinecard
CAS Number: 24584-09-6
Possible CAS #: NA
Molecular form.: C₁₁H₁₆N₄O₄
Appearance: Pale Yellow solid
Melting Point: 188-193°C
Mol. Weight: 268.27
Storage: Refrigerator
Solubility: DMSO (Slightly), Methanol (Slightly, Sonicated), Water
Stability: No Data Available
Category: Amines, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Pfizer Compounds
Boiling Point: No Data Available
Applications: Dexrazoxane is a cardioprotective compound against anthracyclines. It is highly protective in reducing anthracycline-induced cardiotoxicity and extravasation injury. It functions by inhibiting topoisomerase II without inducing DNA strand breaks. Dexrazoxane is a + enantiomer of razoxane.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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