Des-(N-butyn-1-yl) N-(Buta-1,2-Dien-1-yl) Linagliptin (Linagliptin Diene Impurity)

Catalogue number: D289685
Chemical name: Des-(N-butyn-1-yl) N-(Buta-1,2-Dien-1-yl) Linagliptin (Linagliptin Diene Impurity)
Synonyms: 8-((R)-3-Aminopiperidin-1-yl)-7-(buta-1,2-dien-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione;
CAS Number: NA
Possible CAS #: NA
Molecular form.: C₂₅H₂₈N₈O₂
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 472.54
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Amines, Aromatics, Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: Des-(N-butyn-1-yl) N-(Buta-1,2-Dien-1-yl) Linagliptin is an impurity in the synthesis of Linagliptin (L465900), a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes.
References: Prabavathy, N. et al.: Int. J. Pharm. Bio. Sci., 2, 438 (2011); Deacon, C.F.: Diab. Obes. Metab., 13, 7 (2011);
Dangerous Goods Info: NA

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