Desethyl Sacubitril

Catalogue number: D288245
Chemical name: Desethyl Sacubitril
Synonyms: [S-(R*,S*)]-γ-[(3-Carboxy-1-oxopropyl)amino]-α-methyl-[1,1’-Biphenyl]-4-pentanoic Acid; (2R,4S)-4-[(3-Carboxy-1-oxopropyl)amino]-4-[(p-phenylphenyl)methyl]-2-methylbutanoic Acid; (2R,4S)-5-(Biphenyl-4-yl)-4-[(3-carboxypropionyl)amino]-2-methylpentanoic Acid; Sacubitrilat; LBQ 657
CAS Number: 149709-44-4
Possible CAS #: NA
Molecular form.: C₂₂H₂₅NO₅
Appearance: White Solid
Melting Point: 166-168°C
Mol. Weight: 383.44
Storage: Refrigerator
Solubility: DMSO (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: No Data Available
Boiling Point: No Data Available
Applications: Desethyl Sacubitril is an impurity in the synthesis of Sacubitril (S080895), an antihypertensive drug used in combination with valsartan. The combination drug, valsartan/sacubitril, known during trials as LCZ696 and marketed under the brand name, Entresto, is a treatment for heart failure.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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5mg $265.00
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25mg $960.00
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Exact Weight Packaging ($75(USD) / Vial)
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