2’-Deoxy-6-thio Guanosine-13C, 15N2

Catalogue number: D281652
Chemical name: 2’-Deoxy-6-thio Guanosine-13C, 15N2
Synonyms: 2-Amino-9-(2-deoxy-β-D-erythro-pentofuranosyl)-9H-purine-6(1H)-thione-13C, 15N2; 2-Amino-9-(2-deoxy-β-D-erythro-pentofuranosyl)-6-mercaptopurine-13C, 15N2; 2’-Deoxythioguanosine-13C, 15N2; 2’-Desoxy-6-thioguanosine-13C, 15N2; NSC 71261-13C, 15N2; TGdR-13C, 15N2; Thioguanine Deoxyriboside-13C, 15N2; β-Thioguanine Deoxyriboside-13C, 15N2
CAS Number: NA
Possible CAS #: NA
Molecular form.: C₉¹³CH₁₃N₃¹⁵N₂O₃S
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 286.29
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: No Data Available
Boiling Point: No Data Available
Applications: 2’-Deoxy-6-thio Guanosine-13C, 15N2 is labelled 2’-Deoxy-6-thio Guanosine (D281650) which is a Guanosine (G837900) derivative with cancer chemotherapeutic properties. It is involved in the inhibition of human RNase H-mediated RNA cleavage from DNA-RNA duplexes via incorporation into DNA.
Dangerous Goods Info: NA
References: Momparler, R.L. et al.: Cancer Treat. Rep., 62, 135 (1978); Krynetskaia, N.F. et al.: Mol. Pharmacol., 56, 841 (1999)
Peer Review Product Citations:

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