rac-2-Deoxy-D-erythro-pentofuranose 3,5-Di-p-toluate (Decitabine Impurity)

Catalogue number: D232855
Chemical name: rac-2-Deoxy-D-erythro-pentofuranose 3,5-Di-p-toluate (Decitabine Impurity)
Synonyms: p-Toluic Acid 3,5-Diester with 2-Deoxy-D-erythro-pentofuranose
CAS Number: 17117-72-5
Possible CAS #: NA
Molecular form.: C₂₁H₂₂O₆
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 370.4
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: 2-Deoxy-D-erythro-pentofuranose 3,5-di-p-toluate is an impurity of Decitabine (α-isomer: D226730), a DNA hypomethylating agent that is used to treat various forms of cancer, such as myelogeneous leukemia and metastatic lung cancerBy inhibiting DNA methyltransferase, Decitabine silences the tumour suppressor genes and, consequently, “normalizing” gene expression in cancerous cells.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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