O-De(3-fluorobenzyl) Lapatinib Ditosylate Salt

Catalogue number: D228750
Chemical name: O-De(3-fluorobenzyl) Lapatinib Ditosylate Salt
Synonyms: 2-Chloro-4-[[6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-4-quinazolinyl]amino]phenol Ditosylate;
CAS Number: NA
Possible CAS #: 1268997-70-1-free base
Molecular form.: C₃₆H₃₇ClN₄O₁₀S₃
Appearance: Yellow Solid
Melting Point: >176°C (dec.)
Mol. Weight: 817.35
Storage: -20˚C Freezer
Solubility: DMSO, Methanol
Stability: No Data Available
Category: Aromatics, Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
Boiling Point: No Data Available
Applications: A reactive metabolite of Lapatinib (L175800) which is associated with various drug toxicities. Lapatinib is metabolized mainly by P450 3A4 to form O- and N-dealkylated metabolites.
Dangerous Goods Info: NA
References: He, K., et al.: Chem. Res. Toxicol., 11, 252 (1998), Rusnuk, D., et al.: Cancer Res., 61, 7196 (2001), Li, X., et al.: Drug Metab. Dispos., 37, 1242 (2009),
Peer Review Product Citations:

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  Pack size Price(USD)
2.5mg $160.00
  Pack size Price(USD)
25mg $1280.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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