Catalogue number: D228735
Chemical name: Defluoro-Canagliflozin
Synonyms: (1S)-1,​5-​Anhydro-​1-​C-​[4-​methyl-​3-​[(5-​phenyl-​2-​thienyl)​methyl]​phenyl]​-D-​glucitol, ​,
CAS Number: 842133-16-8
Possible CAS #: NA
Molecular form.: C₂₄H₂₆O₅S
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 426.53
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: No Data Available
Boiling Point: No Data Available
Applications: Defluoro-Canagliflozin is an impurity of Canagliflozin (C175190), a sodium/glucose cotransporter 2 (SGLT2) inhibitor. Canagliflozin has been shown to dose dependently reduce calculated renal threshold for glucose excretion and increase urinary glucose excretion. Canagliflozin is a candidate for the treatment of type 2 diabetes and obesity.
Dangerous Goods Info: NA
References: Chao, E. et al.: Drug Fut., 36, 351 (2011); Sha, S. et al.: Diab. Obes. Metab., 13, 669 (2011); Kipnes, M.S.: Clin. Invest., 1, 145 (2011);
Peer Review Product Citations:

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