Catalogue number: D212110
Chemical name: (6aR,12aR,12bS)-1,3,4,4a,5,6,6a,12,12a,12b-Decahydro-10-hydroxy-4,4,6a,12b-tetramethyl-2H-benzo[a]xanthene-8,11-dione
CAS Number: 1258005-85-4
Possible CAS #: NA
Molecular form.: C₂₁H₂₈O₄
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 344.44
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Inhibitors
Boiling Point: No Data Available
Applications: (6aR,12aR,12bS)-1,3,4,4a,5,6,6a,12,12a,12b-Decahydro-10-hydroxy-4,4,6a,12b-tetramethyl-2H-benzo[a]xanthene-8,11-dione is an analog of (4aS,6aS,12aR,12bS)-1,3,4,4a,5,6,6a,12,12a,12b-Decahydro-9-(hydroxymethyl)-4,4,6a,12b-tetramethyl-2H-benzo[a]xanthene-8,11-dione (BE 40644) which is a new human thioredoxin system inhibitor. Be 40644 shows the ability to inhibit the growth of several cancer cell lines.
Dangerous Goods Info: NA
References: Torigoe, K., et al.: J. Antibiot., 49, 314 (1996); Ishii, S., et al.: Chem. Pharm. Bull., 57, 1103 (2009)
Peer Review Product Citations:

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