(S)-N-Deacetyl Colchicine

Catalogue number: D198920
Chemical name: (S)-N-Deacetyl Colchicine
Synonyms: (7S)-7-Amino-6,7-dihydro-1,2,3,10-tetramethoxy-benzo[a]heptalen-9(5H)-one; (-)-7-Deacetylcolchicine; NSC 201400;
CAS Number: 3476-50-4
Possible CAS #: NA
Molecular form.: C₂₀H₂₃NO₅
Appearance: Light Yellow to Yellow Solid
Melting Point: 80-85°C
Mol. Weight: 357.4
Storage: -20°C Freezer, Under Inert Atmosphere
Solubility: Chloroform, DMSO, Methanol
Stability: No Data Available
Category: Amines, Chiral Reagents, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.
Dangerous Goods Info: Not a dangerous good if item is equal too or less than 1g/ml and there is less than 100g in the package
References: Lunduena, R.F., et al.: Curr. Opin. Cell Biol., 4, 53 (1992), Ceccatelli, S., et al.: Neuroreport, 8, 3779 (1997), Want, T.H., et al.: J. Biol. Chem., 273, 4928 (1998), Andreu, J.M., et al.: Biochemistry, 37, 8356 (1998), Jordan, A., et al.: Med. Res. Rev., 18, 259 (1998), Alali, F., et al.: Phytochem. Anal., 19, 385 (2008), Chang, D., et al.: Bioorg. Med. Chem. Lett., 19, 4416 (2009),
Peer Review Product Citations:

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50mg $285.00
250mg $1200.00
  Pack size Price(USD)
25mg $150.00
100mg $565.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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