Catalogue number: D193410
Chemical name: Darglitazone
Synonyms: 5-[[4-[3-(5-Methyl-2-phenyl-4-oxazolyl)-1-oxopropyl]phenyl]methyl]-2,4-thiazolidinedione; (±)-5-[[4-[3-(5-Methyl-2-phenyl-4-oxazolyl)-1-oxopropyl]phenyl]methyl]-2,4-Thiazolidinedione; (±)-5-[p-[3-(5-Methyl-2-phenyl-4-oxazolyl)propionyl]benzyl]-2,4-thiazolidinedione CP 86325;
CAS Number: 141200-24-0
Possible CAS #: NA
Molecular form.: C₂₃H₂₀N₂O₄S
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 420.48
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: No Data Available
Boiling Point: No Data Available
Applications: Darglitazone is a TZD (thiazolidinedione) that increases the sensiticirt od clls to insulin, stimulating insulin-induced P13K activity at submicromolar concentrations. It increases insulin effectiveness in diabetes mellitus subjects.
Dangerous Goods Info: NA
References: Wilson, T> et al.: J. Med. Chem., 39, 665 (1996); Zhang, B. et al.: J. Biol. Chem., 269, 25735 (1994);
Peer Review Product Citations:

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