Dabrafenib Mesylate

Catalogue number: D101005
Chemical name: Dabrafenib Mesylate
Synonyms: GSK 2118436 Methanesulfonate Salt; GSK 2118436B; N-[3-[5-(2-Amino-4-pyrimidinyl)-2-(1,1-dimethylethyl)-4-thiazolyl]-2-fluorophenyl]-2,6-difluoro-benzenesulfonamide Methanesulfonate
CAS Number: 1195768-06-9
Possible CAS #: NA
Molecular form.: C₂₄H₂₄F₃N₅O₅S₃
Appearance: White Solid
Melting Point: >234ºC (dec.)
Mol. Weight: 615.67
Storage: Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility: DMSO (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: No Data Available
Boiling Point: No Data Available
Applications: Dabrafenib is an inhibitor of mutated BRAF kinase and has clinical activity with a manageable safety profile in clinical trials of phase 1 and 2 in patients with BRAF(V600)-mutated metastatic melanoma.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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