(3S)-3-Cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile (ent-Ruxolitinib)

Catalogue number: C988940
Chemical name: (3S)-3-Cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile (ent-Ruxolitinib)
Synonyms: (βS)-β-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrile
CAS Number: 941685-37-6
Possible CAS #: NA
Molecular form.: C₁₇H₁₈N₆
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 306.37
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: (3S)-3-Cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile is a newly developed JAK2 inhibitor therapy aimed to improve MPN-associated splenomegaly and systemic symptoms. The opposite enantiomer of Ruxolitinib (R702000).
Dangerous Goods Info: NA
References: Koppikar, P., et al.: Nature., 489, 155 (2012); Ratcliffe, A.J., et al.: Drug. Discover. Series., 19, 218 (2012);
Peer Review Product Citations:

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