11-Cyclopropyl-5,11-dihydro-4-(hydroxymethyl)-6H-dipyrido[3,2-b:2’,3’-e][1,4] diazepin-6-one

Catalogue number: C988365
Chemical name: 11-Cyclopropyl-5,11-dihydro-4-(hydroxymethyl)-6H-dipyrido[3,2-b:2’,3’-e][1,4] diazepin-6-one
Synonyms: 12-Hydroxy Nevirapine;
CAS Number: 133627-24-4
Possible CAS #: NA
Molecular form.: C₁₅H₁₄N₄O₂
Appearance: Light Yellow Solid
Melting Point: >184ºC (dec.)
Mol. Weight: 282.3
Storage: Refrigerator
Solubility: DMSO (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: Anti-virals, Inhibitors, Non-nucleoside Reverse Transcriptase, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: 11-Cyclopropyl-5,11-dihydro-4-(hydroxymethyl)-6H-dipyrido[3,2-b:2’,3’-e][1,4]diazepin-6-one, is a metabolite of Nevirapine (N391275), which is a potent (IC50=84nM) and selective non-nucleoside inhibitor of HIV-1 reverse transcriptase. It is also an antiviral.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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