[SP-4-2-(1R-trans)]-(1,2-Cyclohexanediamine-N,N’) Dichloridoplatinum(II)

Catalogue number: C987465
Chemical name: [SP-4-2-(1R-trans)]-(1,2-Cyclohexanediamine-N,N’) Dichloridoplatinum(II)
Synonyms: [SP-4-2-(1R-trans)]-Dichloro(1,2-cyclohexanediamine-N,N’)platinum; (SP-4-2)-Dichloro[(1R,2R)-1,2-cyclohexanediamine-κN,κN’]platinum; (1R-trans)-1,2-Cyclohexanediamine Platinum Complex; Dichloro((1R,2R)-trans-diaminocyclohexane)platinum(II); Dichloro((R,R)-1,2-diaminocyclohexane)platinum; Dichloro(1R,2R-1,2-diaminocyclohexane)platinum; Dichloro(1R,2R-cyclohexanediammine)platinum(II); Dichloro(trans-R,R-1,2-diaminocyclohexane)platinum; Dichloro(trans-l-1,2-cyclohexanediamine)platinum(II); Dichloro[(1R,2R)-1,2-cyclohexanediamine]platinum; Dichloro[(R,R)-1,2-cyclohexanediamine]platinum; Dichloro[trans-(-)-1,2-cyclohexanediamine]platinum(II); NSC 265460; [SP-4-2-[1R-(trans)]]-Dichloro(1,2-cyclohexanediamine-κN,κN’)-platinum; cis-Dichlorobis((1R,2R)-cyclohexanediamine)platinum
CAS Number: 61848-66-6
Possible CAS #: NA
Molecular form.: C₆H₁₄Cl₂N₂Pt
Appearance: Yellow Solid
Melting Point: >256°C (dec.)
Mol. Weight: 380.18
Storage: Refrigerator, under inert atmosphere
Solubility: DMSO
Stability: No Data Available
Category: Amines, Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: [SP-4-2-(1R-trans)]-(1,2-Cyclohexanediamine-N,N’) dichloridoplatinum(II) is an impurity of Oxiplatin (O845075), third generation platinum complex. An antitumor agent with activity against colorectal cancer. Cytotoxicity follows the formation of adducts with DNA. Antineoplastic.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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