[SP-4-2-(1R-trans)]-(1,2-Cyclohexanediamine-κN,κN’) Diiodoplatinum

Catalogue number: C984525
Chemical name: [SP-4-2-(1R-trans)]-(1,2-Cyclohexanediamine-κN,κN’) Diiodoplatinum
Synonyms: (SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-κN,κN’]diiodoplatinum; (1R-trans)-1,2-Cyclohexanediamine Platinum Complex; (trans-1R,2R-1,2-Diaminocyclohexane)diiodoplatinum; (trans-R,R-1,2-Diaminocyclohexane)diiodoplatinum; (trans-R,R-Cyclohexane-1,2-diamine)diiodoplatinum; Diiodo(trans-l-1,2-cyclohexanediamine)platinum; NSC 290127; [SP-4-2-(1R-trans)]-(1,2-cyclohexanediamine-N,N’)diiodoplatinum; USP Oxiplatin Related Compound F;
CAS Number: 66845-32-7
Possible CAS #: NA
Molecular form.: C₆H₁₄I₂N₂Pt
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 563.08
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Amines, Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: [SP-4-2-(1R-trans)]-(1,2-Cyclohexanediamine-κN,κN’)diiodoplatinum is a potential antitumor agent. Impurity of Oxiplatin (O845075), third generation platinum complex. An antitumor agent with activity against colorectal cancer. Cytotoxicity follows the formation of adducts with DNA. Antineoplastic.
Dangerous Goods Info: NA
References: Kidani, Y. et al.: Biomed. Pharmacther., 43, 261 (1989); Noji, M. et al.: J. Med. Chem., 24, 508 (1981); Kidani, Y., et al.: J. Med. Chem., 21, 1315 (1978), Kizu, R., et al.: Cancer Chemother. Pharmacol., 31, 475 (1993), Levi, F., et al.: Eur. J. Cancer, 29A, 1280 (1993), Simpson, D., et al.: Drugs, 63, 2127 (2003),
Peer Review Product Citations:

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