Catalogue number: C838500
Chemical name: Curcumin
Synonyms: (1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione; (E,E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione; C Yellow 15; C.I. 75300; C.I. Natural Yellow 3; Curcuma; Curcumin I; Curcumine; Diferuloylmethane; Haidr; Halad; Haldar; Ukon;
CAS Number: 458-37-7
Possible CAS #: NA
Molecular form.: C₂₁H₂₀O₆
Appearance: Bright Orange Solid
Melting Point: >180°C (dec.)
Mol. Weight: 368.38
Storage: Refrigerator
Solubility: DMSO (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: Aromatics, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: A natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and antioxidant properties. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IκB kinase. Inhibits inducible nitric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelope. Curcumin is currently being examined as a possible therapeutic for the treatment of Alzheimers disease (Chem. and Eng. News 90(31), 44 (2012)).
Dangerous Goods Info: NA
References: Srinivasan, et al.: J. Pharm. Pharmacol., 5, 448 (1953), Tu, B., et al.: J .Cell Biol., 164, 341 (2004), Xu, G., et al.: Biochemistry, 44, 9817 (2005), Johnson, J., et al.: Cancer Lett., 255, 170 (2007), Chem. and Eng. News 90(31), 44 (2012)
Peer Review Product Citations:

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5g $55.00
25g $110.00
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10g $60.00
50g $195.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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