CP-154526 Hydrochloride

Catalogue number: C781295
Chemical name: CP-154526 Hydrochloride
Synonyms: N-Butyl-N-ethyl-2,5-dimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine Hydrochloride ; CP 154526 Hydrochloride ;
CAS Number: 257639-98-8
Possible CAS #: 157286-86-7-free base
Molecular form.: C₂₃H₃₃ClN₄
Appearance: Pale Yellow Solid
Melting Point: 167-169°C
Mol. Weight: 400.99
Storage: Refrigerator
Solubility: DMSO, Methanol
Stability: No Data Available
Category: Amines, Aromatics, Heterocycles, Neurochemicals, Pfizer Compounds, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: A selective, non-peptide antagonist of corticotropin releasing factor receptors (CRF1). It blocks CRF-induced adenylate cyclase activation and attenuates activation of the HPA axis by CRF. It displayed anxiolytic-like activity in the rat elevated plus-maze test; brain penetrant.
Dangerous Goods Info: NA
References: Lundkist, J. et al.: Eur. J. Pharmacol., 309, 195 (1996); Arbolius, L. et al.: J. pharmacol. Exp. Therap., 294, 588 (2000); Kehne, J.H. et al.: Neuropharmacol., 39, 1357 (2000);
Peer Review Product Citations:

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  Pack size Price(USD)
5mg $70.00
25mg $265.00
100mg $880.00
  Pack size Price(USD)
10mg $125.00
50mg $495.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   Pending QC

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