Combretastatin A4

Catalogue number: C643000
Chemical name: Combretastatin A4
Synonyms: (Z)-2-Methoxy-5-[2-(3,4,5-trimethoxyphenyl)ethenyl]phenol, 3,4,5-Trimethoxy-3’-hydroxy-4’-methoxy-(Z)-stilbene; CS-A4;
CAS Number: 117048-59-6
Possible CAS #: NA
Molecular form.: C₁₈H₂₀O₅
Appearance: Off-White to Pale Beige Solid
Melting Point: 113-116°C
Mol. Weight: 316.35
Storage: -20°C Freezer
Solubility: Chloroform, Ethyl Acetate, Methanol
Stability: No Data Available
Category: Inhibitors
Boiling Point: No Data Available
Applications: Combretastatin is a small organic molecule found in the bark of the African bush willow tree Combretum caffrum. Combretastatin-A4 Prodrug Induces Mitotic Catastrophe in Chronic Lymphocytic Leukemia Cell Line Independent of Caspase Activation and Poly(ADP-ribose) Polymerase Cleavage. A potent cytotoxic agent which strongly inhibits the polymerization of tubulin by binding to the colchicine site.
Dangerous Goods Info: Not a dangerous good if item is equal too or less than 1g/ml and there is less than 100g in the package
References:
Peer Review Product Citations:

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  Pack size Price(USD)
5mg $45.00
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25mg $195.00
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100mg $575.00
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  Pack size Price(USD)
10mg $85.00
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50mg $370.00
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250mg $895.00
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Exact Weight Packaging ($75(USD) / Vial)
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Inventory Status:   In Stock

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