Catalogue number: C640006
Chemical name: iso-Colchicine-d3
Synonyms: N-[(7S)-5,6,7,10-Tetrahydro-1,2,3,9-tetramethoxy-10-oxobenzo[a]heptalen-7-yl]acetamide; Isocolchicine;
CAS Number: 1246818-69-8
Possible CAS #: unlabelled: 518-12-7
Molecular form.: C₂₂H₂₂D₃NO₆
Appearance: Faintly Yellow Crystalline Powder
Melting Point: 148-153°C
Mol. Weight: 402.46
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Chiral Reagents, Inhibitors, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: An isotopically labelled antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.
Dangerous Goods Info: Not a dangerous good if item is equal too or less than 1g/ml and there is less than 100g in the package
References: Lunduena, R.F., et al.: Curr. Opin. Cell Biol., 4, 53 (1992), Ceccatelli, S., et al.: Neuroreport, 8, 3779 (1997), Want, T.H., et al.: J. Biol. Chem., 273, 4928 (1998), Andreu, J.M., et al.: Biochemistry, 37, 8356 (1998), Jordan, A., et al.: Med. Res. Rev., 18, 259 (1998),
Peer Review Product Citations:

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  Pack size Price(USD)
5mg $125.00
  Pack size Price(USD)
50mg $1000.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   Pending QC

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