Clasto-lactacystin (Omuralide)

Catalogue number: C562500
Chemical name: Clasto-lactacystin (Omuralide)
Synonyms: (1R,4R,5S)-1-[(1S)-1-Hydroxy-2-methylpropyl]-4-methyl-6-oxa-2-azabicyclo[3.2.0]heptane-3,7-dione; Clasto-lactacystin β-Lactone; Omuralide
CAS Number: 154226-60-5
Possible CAS #: NA
Molecular form.: C₁₀H₁₅NO₄
Appearance: White Solid
Melting Point: 186-187°C
Mol. Weight: 213.23
Storage: -20°C Freezer
Solubility: DMF, Ethanol, Hot Ethyl Acetate, Methanol, Pyridine
Stability: No Data Available
Category: Inhibitors
Boiling Point: No Data Available
Applications: A cell permeable, irreversible proteasome inhibitor. It is 20-fold more potent than Lactacystin. Lactacytstin spontaneously converts to clasto-lactacystin in biological systems. Clasto-lactacystin is the only cell permeable form of lactacystin. Induces neurite growth and inhibits cell cycle progression similar to lactacytin.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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