CK-2-68

Catalogue number: C540000
Chemical name: CK-2-68
Synonyms: 7-Chloro-3-methyl-2-[4-[[4-(trifluoromethoxy)phenyl]methyl]phenyl]-4(1H)-quinolinone
CAS Number: 1361004-87-6
Possible CAS #: NA
Molecular form.: C₂₄H₁₇ClF₃NO₂
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 443.85
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: No Data Available
Boiling Point: No Data Available
Applications: CK-2-68 has antimalarial activity against the 3D7 strain of P. falciparum of 36 nM, is selective for PfNDH2 over other respiratory enzymes (inhibitory IC50 against PfNDH2 of 16 nM), and demonstrates low cytotoxicity and high metabolic stability in the presence of human liver microsomes.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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