Catalogue number: C432727
Chemical name: CI-992-d8
Synonyms: N-(4-Morpholinylsulfonyl)-L-phenylalanyl-3-(2-amino-4-thiazolyl)-N-[(1S,2R,3S)-1-(cyclohexylmethyl)-2,3-dihydroxy-5-methylhexyl]-L-alaninamide-d8; [1S-(1R*,2S*,3R*)]- N-(4-morpholinylsulfonyl)-L-phenylalanyl-3-(2-amino-4-thiazolyl)-N-[1-(cyclohexylmethyl)-2,3-dihydroxy-5-methylhexyl]-L-alaninamide-d8; PD 134672-d8;
CAS Number: NA
Possible CAS #: Unlabeled: 135704-06-2
Molecular form.: C₃₆H₅₂D₈N₆O₇S₂
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 761.08
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Amines, Chiral Reagents, Isotope Labeled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
Boiling Point: No Data Available
Applications: CI-992-d8, is the labeled analogue of CI-992 (C432725), which is a novel potent orally active renin inhibitor, that has been proved to be effective on blood pressure on normotensive and hypertensive monkeys. It is also a derivative of Zankiren (Z148060).
Dangerous Goods Info: NA
References: Ryan, M. J., et al.: J. Pharmaco. Exp. Therap., 268, 372 (1994);
Peer Review Product Citations:

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