CI-988

Catalogue number: C432695
Chemical name: CI-988
Synonyms: 4-[[(1R)-2-[[(2R)-3-(1H-Indol-3-yl)-2-methyl-1-oxo-2-[[(tricyclo[3.3.1.13,7]dec-2-yloxy)carbonyl]amino]propyl]amino]-1-phenylethyl]amino]-4-oxobutanoic Acid; CI 988; [R-(R*,R*)]-4-[[2-[[3-(1H-Indol-3-yl)-2-methyl-1-oxo-2-[[(tricyclo[3.3.1.13,7]dec-2-yloxy)carbonyl]amino]propyl]amino]-1-phenylethyl]amino]-4-oxobutanoic Acid;
CAS Number: 130332-27-3
Possible CAS #: NA
Molecular form.: C₃₅H₄₂N₄O₆
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 614.73
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Heterocycles, Indole Derivatives, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: CI-988 is a potent and selective cholecystokinin 2 (CCK-2) receptor antagonist that displays ~ 1600-fold selectivity over CCK1 receptors and has negligible affinity at other binding sites. CI-988 exhibits anxiolytic activity following oral administration. CI-98 inhibited the proliferation of small cell lung cancer (SCLC) cells in mice.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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